As a result of a shared strategic vision among the coordinators and driven by a strategic intent from the previous 4 Units, RISE-Health is based at the Faculty of Medicine of the University of Porto (FMUP) and encompasses 16 other management centres, of which 5 are at U.Porto (ICBAS, FCUP, FFUP, FMDUP, FCNAUP), and the others are located across various academic units within other institutions, nationwide. 

This extensive research ecosystem engages 5 other public universities (U.Porto, UBI, UTAD, UAlg, University of Aveiro, and University of Madeira), 2 private higher education institutions (University of Fernando Pessoa and University Portucalense), and 3 nursing schools (ESEP, Santa Maria, Santarém) and ESS-IPP.