tl1

Clinical and Translational Research in Cardiovascular Diseases

Coordinated by Adelino Leite-Moreira, TL1 focuses on clinical and translational research in cardiovascular diseases, which remain the leading cause of death and disability in Portugal and European countries. 

This thematic line bridges a national gap in clinical and translational research in this field, pursuing a strategy of bringing together basic and clinical researchers, data scientists, engineers, and other collaborators. 

Towards shared lab facilities and resources and benefiting from a strong collaboration with hospitals and biobank storage, TL1 aims to cover a wide range of topics and establish a broader integrative perspective through a bench-to-bedside-to-bench approach.

Adelino
Leite-Moreira

Adelino Leite-Moreira coordinates RISE-Health’s Thematic Line 1 – Clinical and Translational Research in Cardiovascular Diseases. He is a Full Professor of Physiology & Cardiothoracic Surgery at the Faculty of Medicine of the University of Porto (FMUP), Head of the Department of Physiology and Cardiothoracic Surgery, and President of the Scientific Council. At FMUP, he had been the Coordinator of the Cardiovascular R&D Centre (UnIC). 

He graduated as a medical doctor in 1989 at FMUP and trained as a research fellow from 1991 to 1994 at the Department of Physiology and Medicine of the University of Antwerp, Belgium, where he developed his interest in the field of diastolic function and heart failure with preserved ejection fraction. It was in this field that he defended his PhD thesis in 1997.

In 2003, he completed his clinical training as a cardiothoracic surgeon at the Hospital of São João, where he is currently a Senior Consultant of Cardiothoracic Surgery.

He has a special interest in surgical and technical innovation and holds expertise in the fields of reconstructive mitral and aortic valves surgery, aortic and aortic root surgery, less invasive surgery, as well as in total arterial off-pump coronary artery bypass graft surgery.

Besides cardiothoracic surgery, diastolic function, and heart failure, his research interests also include right ventricular function and pulmonary hypertension. 

Over the years, he authored more than 400 full papers in prestigious international journals, was granted more than 12 million € on competitive calls, and was awarded several major scientific prizes. 

Groups

João Pedro Ferreira

Heart Failure and Myocardial Remodeling

Amândio Rocha Sousa

Integrative Vascular Research

Inês Falcão Pires

Metabolism and Cardiovascular Risk

Ricardo Fontes de Carvalho

Cardiovascular Diagnosis, Signal and Imaging Technologies

Roberto Roncon de Albuquerque​

Innovation and Development in Cardiovascular Intervention