{"id":7308,"date":"2026-10-15T10:19:26","date_gmt":"2026-10-15T09:19:26","guid":{"rendered":"https:\/\/rise-health.pt\/?p=7308"},"modified":"2026-10-16T17:25:52","modified_gmt":"2026-10-16T16:25:52","slug":"novo-laboratorio-de-biomarcadores-promete-acelerar-investigacao-e-cuidados-de-saude","status":"publish","type":"post","link":"https:\/\/rise-health.pt\/pt-pt\/2026\/10\/15\/novo-laboratorio-de-biomarcadores-promete-acelerar-investigacao-e-cuidados-de-saude\/","title":{"rendered":"Novo Laborat\u00f3rio de Biomarcadores promete acelerar investiga\u00e7\u00e3o e cuidados de sa\u00fade"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"7308\" class=\"elementor elementor-7308\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-96c1d45 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"96c1d45\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0a1baba\" data-id=\"0a1baba\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5bbab76 elementor-widget elementor-widget-heading\" data-id=\"5bbab76\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Novo Laborat\u00f3rio de Biomarcadores promete acelerar investiga\u00e7\u00e3o e cuidados de sa\u00fade<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-70975945 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"70975945\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6729ebf2\" data-id=\"6729ebf2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5d946cdb elementor-widget elementor-widget-text-editor\" data-id=\"5d946cdb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Unidade de Investiga\u00e7\u00e3o RISE-Health e FMUP disponibilizam plataforma cient\u00edfica de vanguarda com impacto na pr\u00e1tica cl\u00ednica.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4734a99 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4734a99\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2dd3bbb\" data-id=\"2dd3bbb\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d5e316f elementor-widget elementor-widget-image\" data-id=\"d5e316f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"750\" height=\"500\" src=\"https:\/\/rise-health.pt\/wp-content\/uploads\/2026\/10\/Foto_bio_sigarra.jpg\" class=\"attachment-full size-full wp-image-7310\" alt=\"\" srcset=\"https:\/\/rise-health.pt\/wp-content\/uploads\/2026\/10\/Foto_bio_sigarra.jpg 750w, https:\/\/rise-health.pt\/wp-content\/uploads\/2026\/10\/Foto_bio_sigarra-300x200.jpg 300w\" sizes=\"(max-width: 750px) 100vw, 750px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Fotografia: Faculdade de Medicina da Universidade do Porto - Unidade de Gest\u00e3o de Comunica\u00e7\u00e3o<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-15b4243 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"15b4243\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-cc632e6\" data-id=\"cc632e6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4ff0561 elementor-widget elementor-widget-text-editor\" data-id=\"4ff0561\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p dir=\"ltr\">\u00a0<\/p><p>Ser\u00e1 inaugurado, na Faculdade de Medicina da Universidade do Porto (FMUP), um novo <strong>Laborat\u00f3rio de Biomarcadores<\/strong> (Biomarkers 360) que promete alavancar e acelerar a investiga\u00e7\u00e3o e a presta\u00e7\u00e3o de cuidados de sa\u00fade em Portugal.<\/p><p>A cerim\u00f3nia ir\u00e1 decorrer no dia 21 de outubro, pelas 11h00, contando com a presen\u00e7a do diretor da <strong>Unidade de Investiga\u00e7\u00e3o RISE-Health<\/strong> (sediada na FMUP), <strong>Fernando Schmitt<\/strong>, do diretor da Faculdade de Medicina da Universidade do Porto, <strong>Altamiro da Costa Pereira<\/strong>, do diretor eleito, <strong>Roberto Roncon de Albuquerque<\/strong>, entre outros representantes institucionais e entidades convidadas.<\/p><p>Financiada pelo <strong><a href=\"https:\/\/recuperarportugal.gov.pt\/\" target=\"_blank\" rel=\"noopener\">Plano de Recupera\u00e7\u00e3o e Resili\u00eancia (PRR)<\/a><\/strong> em cerca de <strong>2,1 milh\u00f5es de euros<\/strong>, esta nova plataforma cient\u00edfica disp\u00f5e de estruturas e tecnologia de \u00faltima gera\u00e7\u00e3o, com impacto na investiga\u00e7\u00e3o cl\u00ednica e de transla\u00e7\u00e3o, que se tornar\u00e1 mais competitiva, e na liga\u00e7\u00e3o com as institui\u00e7\u00f5es de sa\u00fade.<\/p><p>As aplica\u00e7\u00f5es\u202fv\u00e3o al\u00e9m das doen\u00e7as gen\u00e9ticas e incluem a neurologia, psiquiatria, oncologia e doen\u00e7as infeciosas, oferecendo uma \u201csolu\u00e7\u00e3o 360\u00ba num mesmo local\u201d, da amostra \u00e0 an\u00e1lise de dados, da mol\u00e9cula ao tecido.<\/p><p>\u201cEsta plataforma est\u00e1 muito direcionada para a descoberta de novos biomarcadores e para a an\u00e1lise de biomarcadores j\u00e1 estabelecidos que possam ser utilizados na pr\u00e1tica cl\u00ednica. Espera-se que exista uma repercuss\u00e3o pr\u00e1tica na vida e na sa\u00fade das pessoas\u201d, afirma <strong>Joana Marques, que coordena o Laborat\u00f3rio juntamente com Rita Barros, ambas investigadoras da RISE-Health e da FMUP<\/strong>.<\/p><p>Em destaque est\u00e1 uma <strong>plataforma de imunoensaios<\/strong> com equipamento inovador a n\u00edvel nacional que deteta biomarcadores neurol\u00f3gicos com uma amostra de sangue, urina, l\u00edquido cefalorraquidiano ou outro fluido corporal. Com uma mol\u00e9cula \u00fanica, \u00e9 poss\u00edvel detetar biomarcadores s\u00e9ricos associados a doen\u00e7as neurol\u00f3gicas e neurodegenerativas, como a doen\u00e7a de Alzheimer e a esclerose m\u00faltipla.<\/p><p>A an\u00e1lise r\u00e1pida (em apenas duas a tr\u00eas horas) e fi\u00e1vel destes biomarcadores no sangue, como neurofilamentos leves, prote\u00edna tau fosforilada e beta-amiloide, \u00e9 uma importante ferramenta para perceber, por exemplo, se um tratamento de uma doen\u00e7a neurol\u00f3gica est\u00e1 a ter o efeito desejado, sem depender de exames de imagem, mais caros e exigentes em termos de disponibilidade e recursos.<\/p><p>As vantagens deste equipamento de vanguarda s\u00e3o permitir avaliar o risco, detetar precocemente e avaliar a progress\u00e3o de uma doen\u00e7a neurol\u00f3gica. Como explica Joana Marques, \u201ceste \u00e9 um grande avan\u00e7o e poder\u00e1 ser crucial, nomeadamente quando h\u00e1 casos familiares, para iniciar uma interven\u00e7\u00e3o mais precoce que possa melhorar o progn\u00f3stico da doen\u00e7a\u201d.<\/p><p>Outro equipamento de ponta \u00e9 um <strong>sequenciador de ADN<\/strong> de leitura longa, em tempo real, que deteta diretamente altera\u00e7\u00f5es gen\u00e9ticas ou epigen\u00e9ticas, como metila\u00e7\u00f5es do ADN, o que, at\u00e9 aqui, s\u00f3 era poss\u00edvel de forma indireta. Em outros pa\u00edses, \u201ceste equipamento, acoplado a um supercomputador, est\u00e1 j\u00e1 a ser utilizado para classificar tumores no decurso de cirurgias, o que ajuda o cirurgi\u00e3o a decidir se a resse\u00e7\u00e3o ter\u00e1 de ser mais ou menos invasiva\u201d.<\/p><p>Entre as estrelas deste Laborat\u00f3rio de Biomarcadores est\u00e1 tamb\u00e9m um <strong>\u201crob\u00f4\u201d automatizado<\/strong>, de prepara\u00e7\u00e3o de bibliotecas de sequencia\u00e7\u00e3o de leitura curta, assim como dois sequenciadores de nova gera\u00e7\u00e3o, focados na \u00e1rea da Oncologia, para detetar c\u00e9lulas de tumor circulante a partir de uma simples amostra de sangue (bi\u00f3psia l\u00edquida), sem necessidade de bi\u00f3psia ou cirurgia para remo\u00e7\u00e3o de tecidos.<\/p><p>Tamb\u00e9m o combate \u00e0s doen\u00e7as infeciosas, como a s\u00e9psis, ganha nesta nova plataforma cient\u00edfica um potencial aliado, que ajuda a identificar o agente e a resist\u00eancia a antimicrobianos, para escolher o tratamento adequado. Na chamada \u201csala de cultura celular\u201d, a aposta ser\u00e1 no desenvolvimento de organoides, esp\u00e9cie de mini-\u00f3rg\u00e3os in vitro.<\/p><p>Na \u00e1rea da <strong>Histopatologia<\/strong> registam-se igualmente grandes avan\u00e7os, do cl\u00e1ssico estudo e compara\u00e7\u00e3o de biomarcadores em tecidos ao recente treino e aplica\u00e7\u00e3o de algoritmos de Intelig\u00eancia artificial \u00e0 imagem histol\u00f3gica.<\/p><p>\u201cEm conjunto, estas ferramentas podem ajudar a acelerar a identifica\u00e7\u00e3o de novos biomarcadores e contribuir para diagn\u00f3sticos mais precisos e para o avan\u00e7o de novas abordagens de preven\u00e7\u00e3o e terap\u00eauticas mais personalizadas\u201d, refere Rita Barros.<\/p><p><strong><a href=\"https:\/\/sigarra.up.pt\/fmup\/pt\/noticias_geral.noticias_cont?p_id=F1836971910\/InauguracaoLaboratorioBiomarcadores_Brochura_Compressed_2026%20(1).pdf\">Brochura<\/a><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-699705a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"699705a\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-171296d\" data-id=\"171296d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d10fafe elementor-widget elementor-widget-spacer\" data-id=\"d10fafe\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Cerca de 300 investigadores de todo o pa\u00eds juntaram-se na Faculdade de Medicina da Universidade do Porto (FMUP), no dia 28 de junho, para participarem na 1.\u00aa Reuni\u00e3o de Trabalho da nova Unidade de Investiga\u00e7\u00e3o RISE-Health, nascida da fus\u00e3o de duas Unidades de Investiga\u00e7\u00e3o sediadas na FMUP, o CINTESIS e a UnIC, \u00e0s quais se juntaram o MedInUP e o CICS \u2013 Universidade da Beira Interior.<\/p>\n","protected":false},"author":6,"featured_media":7310,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[152,385,22],"class_list":["post-7308","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias","tag-fmup","tag-laboratorio-de-biomarcadores","tag-rise-health"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Novo Laborat\u00f3rio de Biomarcadores promete acelerar investiga\u00e7\u00e3o e cuidados de sa\u00fade<\/title>\n<meta name=\"description\" content=\"Unidade de Investiga\u00e7\u00e3o RISE-Health e FMUP disponibilizam plataforma cient\u00edfica de vanguarda com impacto na pr\u00e1tica cl\u00ednica.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, 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